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Function by Other individuals, which include Dickey, has demonstrated that upsized mucin secretion during the airways performs in Considerably the same way, involving analogous vesicles (filled with mucin rather than neurotransmitters) and synaptotagmin and collaborating proteins.
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In these mutant mice, secretory cells’ expulsion of mucin was decreased by about 70%, and mucus-plaque formation inside the airway was lowered by Virtually seventy five%, when compared with wild-form mice. Synaptotagmin was Plainly a respectable therapeutic concentrate on.
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